JBCS

Spectroscopic, chemical and biological data published between 1965-2022 on acylphloroglucinol derivatives are compiled in this review.

NOx emission factors of heavy vehicles were measured through a sensor and compared to legislation.

Microfibers of poly(butylene-adipate-co-terephthalate) (PBAT) and poly-(ε-caprolactone) (PCL) containing ibuprofen were obtained by electrospinning technique. The material revealed potential for transdermal application.

A seven-step high yielding process from low cost α-resorcylic acid to obtain deoxyrhapontigenin is presented. Intermediaries for divergent strategies and structures are also obtained in high yields.

This study optimizes and validates liquid-liquid extraction with low temperature purification (LLE-LTP) for the first time to determine tolfenpyrad in water.

Sequenced oxidation of glycerol forming glyceraldehyde, glyceric acid, tartronic acid and mesoxalic acid catalyzed by bimetallic silver and palladium nanoparticles anchored on the cobalt ferrite surface.

Quantitation method to analyze fentanyl and seven analogues in postmortem blood samples by protein precipitation and liquid chromatography-tandem mass spectrometry.

The image presents a vortex-operated plasma reactor, UV-spectra and chemical kinetics data, culminating in the determinant step for HNO_3(aq) production.

Unlocking seasonal fluctuations in the chemical profile of Eugenia punicifolia through ¹H nuclear magnetic resonance and multivariate analysis. Dimethyl sulfoxide (DMSO) leaf extracts revealed distinct chemical profiles and antioxidant activities across seasons, providing insights into the defense mechanisms of the plant.

2-Hydrazinyl-4-(4-methoxyphenyl)thiazole (PD76) intestinal permeability was assessed by means of the comparison of in vitro assay in Caco-2 cells and in silico platforms.

Sodium glyceroxide is a cheap, stable, and safe homogeneous alkaline catalyst for the alcoholysis of triglycerides.

This study investigates the impact of solvent media on the structural and optical behaviors of two isomers of thiazine derivatives. We analyze the effects of relocating the NO₂ group within the isomers and its implications on molecular geometries, optical parameters, and gap energies across different solvent environments. Bond dissociation energy calculations and various analytical insights further contribute to our understanding of these derivatives.

Glycerophospholipid profiles of wild Amazonian fish observed through mass spectrometry by analyzing season (drought and flood) influences.

The alkaloid fractions of Fusaea longifolia showed high anti-Plasmodium activity and moderate cytotoxic activity. Through characterization via liquid chromatography coupled to mass spectrometry (LC-MS/MS) and using molecular networks, these fractions proved to be promising sources of isoquinoline alkaloids. Based on the molecular docking approach, these alkaloids demonstrated inhibition potential against target enzymes of the Plasmodium falciparum parasite.

Pleurotin (left) is a potent inhibitor of the thioredoxin reductase (TrxR) enzyme, a target for cancer chemotherapy. This work proposes a new derivative (right) that is ca. 40% more active against TrxR than pleurotin.

Poly(oxazoline)s coupled hydroxyethyl starch nanocapsules were developed by inverse miniemulsion via interfacial polyaddition in order to create a powerful protein suppressor vehicle.

The machine learning model discriminant analysis by partial least squares (PLS-DA) was capable of predicting the diagnosis of coronavirus disease (COVID-19), human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS), tuberculosis (TB), and HIV/TB co-infection patients with high accuracy and identifying potential biomarkers associated with the diagnosis.